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BONE MORPHOGENETIC PROTEIN 5
Descriptors Found:
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DeCS
Descriptor
English
:
Bone Morphogenetic Protein 5
Descriptor
Spanish
:
Proteína Morfogenética Ósea 5
Descriptor
Portuguese
:
Proteína Morfogenética Óssea 5
Synonyms
English
:
BMP-5
Tree Number:
D12.644.276.954.200.500
D12.776.467.942.200.500
D23.529.942.200.500
Definition
English
:
A bone morphogenetic protein that may play a role in
CARTILAGE
formation. It is a potent regulator of the
growth
of
CHONDROCYTES
and the synthesis of
cartilage
matrix
proteins
. Evidence for its role in
cartilage
formation can be seen in MICE, where genetic
mutations
that cause loss of
bone morphogenetic protein 5
function result in the formation of small malformed ears.
History Note
English
:
2009(1997)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53132
Unique Identifier:
D055417
Occurrence in VHL
:
Similar:
DeCS